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Liquid chromatography–mass spectrometry methods for urinary biomarker detection in metabonomic studies with application to nutritional studies

✍ Scribed by Cristina Legido-Quigley; Cinzia Stella; Francisco Perez-Jimenez; Jose Lopez-Miranda; Jose Ordovas; Jonathan Powell; Frans van-der-Ouderaa; Lisa Ware; John C. Lindon; Jeremy K. Nicholson; Elaine Holmes


Book ID
102772439
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
623 KB
Volume
24
Category
Article
ISSN
0269-3879

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## Abstract This study describes the metabonomic characters of the spontaneously hypertensive rats (SHR) and intervention effects of Ping Gan prescription. Ultra performance LC coupled with Q‐TOF MS (UPLC/MS‐Q‐TOF) was employed to develop a metabonomic method of the plasma of SHR. There was a signi