Liquid chromatographic resolution of epimeric Diels-Alder adducts on silica gel using binary solvent systems

✍ Scribed by Hara, Shoji ;Ohkuma, Toshikazu ;Nagaoka, Hiroto ;Yamada, Yasuji

• Book ID: 102343409
• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: English
• Weight: 143 KB
• Volume: 3
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240030411

✦ Synopsis

Diels-Alder addition has been widely utilized to obtain cyclic intermediates for natural product synthesis. Epimeric adducts are often produced in this reaction and resolution of the mixture is required for stereospecific synthesis.