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Lipoxygenase Pathways in Atherogenesis

✍ Scribed by Lei Zhao; Colin D Funk


Book ID
113926868
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
493 KB
Volume
14
Category
Article
ISSN
1050-1738

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Lipoxygenases (LOXs) form a heterogeneous family of lipid-peroxidizing enzymes, and several LOX-isoforms (12/15-LOX, 5-LOX) have been implicated in atherogenesis. However, the precise role of these enzymes is still a matter of discussion. 12/15-LOXs are capable of oxidizing lipoproteins (low-density