Liposome-mediated gene transfer in rat lung transplantation: A comparison between the in vivo and ex vivo approaches
β Scribed by Carlos H. R. Boasquevisque; Bassem N. Mora; Mariano Boglione; Jon K. Ritter; Ronald K. Scheule; Nelson Yew; Lisa Debruyne; Lihui Qin; Jonathan S. Bromberg; G.Alexander Patterson
- Book ID
- 114063133
- Publisher
- CTSNet
- Year
- 1999
- Tongue
- English
- Weight
- 146 KB
- Volume
- 117
- Category
- Article
- ISSN
- 1097-685X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background We investigated optimum conditions for __ex vivo__ gene transfer into liver grafts by plasmid injection via the portal vein combined with electroporation in rat liver transplantation. ## Methods Anesthetized 9βweekβold male ShionogiβWistar rats were used as donors and r
The lack of a small animal model of hepatitis C virus (HCV) infection has impeded elucidation of the pathogenesis of HCV. The aim of this study was to develop an HCV-expressing animal model by means of cationic liposome-mediated in uiuo gene transfer. To examine the feasibility of this strategy, pAc