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Liposomal glucocorticoids as tumor-targeted anti-angiogenic nanomedicine in B16 melanoma-bearing mice

โœ Scribed by Manuela Banciu; Josbert M. Metselaar; Raymond M. Schiffelers; Gert Storm


Book ID
116698211
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
898 KB
Volume
111
Category
Article
ISSN
0960-0760

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## Abstract The application of tumor necrosis factorโ€ฮฑ (TNF) for the treatment of solid tumors is limited by its severe, lifeโ€threatening, toxicity. Therefore, only low dosages of this cytokine can be applied systemically, which results in poor tumor response. It has been demonstrated previously th