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Liposomal Formulations of Inflammatory Bowel Disease Drugs: LocalversusSystemic Drug Delivery in a Rat Model

✍ Scribed by Filippos Kesisoglou; Simon Yuji Zhou; Susan Niemiec; Jordan Wing Lee; Ellen M. Zimmermann; David Fleisher

Publisher
Springer US
Year
2005
Tongue
English
Weight
369 KB
Volume
22
Category
Article
ISSN
0724-8741

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✍ Harumi Yamada; Hajime Kotaki; Hisao Furitsu; Yasufumi Sawada; Tatsuji Iga πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 166 KB πŸ‘ 1 views

E3040, a new class of anti-inflammatory drug, was found to reduce the plasma uric acid level in the first phase of clinical studies. In the present study, the mechanism of the uricosuric action of E3040 was investigated using the hyperuricemia model rat. The fractional excretion of uric acid (FE ura