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LIPOSOMAL DAUNORUBICIN OVERCOMES DRUG RESISTANCE IN HUMAN BREAST, OVARIAN AND LUNG CARCINOMA CELLS

โœ Scribed by Sadava, David; Coleman, Aaron; Kane, Susan E.


Book ID
118742497
Publisher
Informa plc
Year
2002
Tongue
English
Weight
189 KB
Volume
12
Category
Article
ISSN
0898-2104

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We developed three daunorubicin (D1)-resistant sublines (ML1/I, II, III) from the human myelocytic cell line (ML1). These sublines were 28-, 70- and 162-fold more resistant than sensitive (ML1/S) cells to the cytotoxicity of D1 and were cross-resistant to adriamycin, epiadriamycin, actinomycin D, VP