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Lipopolysaccharide regulates biosynthesis of cystathionine γ-lyase and hydrogen sulfide through toll-like receptor-4/p38 and toll-like receptor-4/NF-κB pathways in macrophages

✍ Scribed by Yijie Zheng, Naixiang Luo, Dongzhen Mu…


Book ID
120891870
Publisher
Society for In Vitro Biology
Year
2013
Tongue
English
Weight
435 KB
Volume
49
Category
Article
ISSN
1475-2689

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Acute exposure to lipopolysaccharide (LPS) can cause hypoglycemia and insulin resistance; the underlying mechanisms, however, are unclear. We set out to determine whether insulin resistance is linked to hypoglycemia through Toll-like receptor-4 (TLR4), myeloid differentiation factor 88 (MyD88), and