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Lipopolysaccharide-inducible Gene Expression Profile in Human Monocytes

✍ Scribed by Hashimoto, Shin-ichi; Morohoshi, Kei; Suzuki, Takuji; Matsushima, Kouji

Book ID
115478920
Publisher
Informa plc
Year
2003
Tongue
English
Weight
152 KB
Volume
35
Category
Article
ISSN
0036-5548

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Bacterial lipopolysaccharide (LPS) has been shown to induce a wide variety of proinflammatory cytokines and chemokines. An initial challenge with minute amounts of LPS causes tolerance to later LPS effects which is characterized by a much lower or abrogated release of pro-inflammatory cytokines. To