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Lipopolysaccharide enhances oxidative modification of low density lipoprotein by copper ions, endothelial and smooth muscle cells

✍ Scribed by Cécile Maziere; Marie-Alix Conte; Françoise Dantin; Jean-Claude Maziere


Book ID
119438285
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
114 KB
Volume
143
Category
Article
ISSN
0021-9150

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It has been proposed that low density lipoprotein (LDL) must undergo oxidative modification before it can participate in atherosclerosis. The present paper studied the effect of cholesterol oxidation in LDL on cultured vascular smooth muscle cells. LDL was oxidized by cholesterol oxidase (3-beta-hyd