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Lipopolysaccharide-Activated B Cells Down-Regulate Th1 Immunity and Prevent Autoimmune Diabetes in Nonobese Diabetic Mice

✍ Scribed by Tian, J.; Zekzer, D.; Hanssen, L.; Lu, Y.; Olcott, A.; Kaufman, D. L.


Book ID
126265908
Publisher
American Association of Immunologists
Year
2001
Tongue
English
Weight
439 KB
Volume
167
Category
Article
ISSN
0022-1767

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## Abstract ## Background Heparanase is an endo‐β‐D‐glucuronidase that cleaves heparan sulfate saccharide chains. The enzyme promotes cell adhesion, migration and invasion, and was shown to play a significant role in cancer metastasis and angiogenesis. ## Methods The present study focuses on the