Enhanced oral bioavailability of doxorub
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Weilun Ke; Yansong Zhao; Rongqin Huang; Chen Jiang; Yuanying Pei
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Article
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2008
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John Wiley and Sons
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English
โ 271 KB
PAMAM dendrimers can permeate across intestinal epithelial barriers suggesting their potential as oral drug carriers. In the present study, we have developed a drug-PAMAM complex for oral administration. The loading of a model drug, doxorubicin into PAMAM, the cellular uptake and pharmacokinetics of