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Lipomer of doxorubicin hydrochloride for enhanced oral bioavailability

โœ Scribed by Derajram M. Benival; Padma V. Devarajan


Book ID
113655707
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
904 KB
Volume
423
Category
Article
ISSN
0378-5173

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PAMAM dendrimers can permeate across intestinal epithelial barriers suggesting their potential as oral drug carriers. In the present study, we have developed a drug-PAMAM complex for oral administration. The loading of a model drug, doxorubicin into PAMAM, the cellular uptake and pharmacokinetics of