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Lipomas have characteristic structural chromosomal rearrangements of 12q13-q14

✍ Scribed by N. Mandahl; S. Heim; B. Johansson; K. Bennet; F. Mertens; G. Olsson; B. Rööser; A. Rydholm; H. Willén; F. Mitelman

Book ID
102863941
Publisher
John Wiley and Sons
Year
1987
Tongue
French
Weight
524 KB
Volume
39
Category
Article
ISSN
0020-7136

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Gains and complex rearrangements of the
Gains and complex rearrangements of the 12q13-15 chromosomal region in ordinary lipomas: The “missing link” between lipomas and liposarcomas?
✍ Antoine Italiano; Nathalie Cardot; Florence Dupré; Isabelle Monticelli; Frédériq 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 394 KB

## Abstract Well‐differentiated liposarcomas (WDLPS) classically contain high‐level amplification of 12q14‐15 sequences, including the __MDM2__ and __CDK4__ genes, while lipomas are characterized by simple structural chromosome aberrations often involving __HMGA2__ at 12q15. Previous studies have s