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Lipoic acid prevents oxidative stress in vitro and in vivo by an acute hyperphenylalaninemia chemically-induced in rat brain

✍ Scribed by Tarsila Barros Moraes; Fernanda Zanin; Andrea da Rosa; Amanda de Oliveira; Juliana Coelho; Felipe Petrillo; Moacir Wajner; Carlos Severo Dutra-Filho

Book ID
119303657
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
425 KB
Volume
292
Category
Article
ISSN
0022-510X

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## Abstract Acrylonitrile (ACN) is a volatile, toxic liquid used as a monomer in the manufacture of synthetic rubber, styrene plastics, acrylic fiber, and adhesives. ACN is a potent neurotoxin. A role for free radical mediated lipid peroxidation in the toxicity of ACN has been suggested. We examine