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Lipoic acid inhibits lipid peroxidation and improves renal function in a model of acute liver failure

✍ Scribed by David Harry; Radhi Anand; Dave Goodier; L.Jackson Roberts; Kevin Moore

Book ID
119527095
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
311 KB
Volume
34
Category
Article
ISSN
0168-8278

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Oxidative mechanisms have been implicated in the pathogenesis of brain edema in acute liver failure (ALF). The aim of this study was to test the hypothesis that inhibition of iron-catalyzed oxidative reactions through iron chelation using deferoxamine could attenuate brain edema in a swine model of