Lipiodolization for unresectable hepatocellular carcinoma: An analysis of 205 patients using univariate and multivariate analysis

✍ Scribed by Keiko Urata; Takashi Matsumata; Tatsuro Kamakura; Kanehiro Hasuo; Keizo Sugimachi

• Publisher: John Wiley and Sons
• Year: 1994
• Tongue: English
• Weight: 458 KB
• Volume: 56
• Category: Article
• ISSN: 0022-4790
• DOI: 10.1002/jso.2930560113

✦ Synopsis

Since 1982 we have developed and successfully performed lipiodolization on 205 patients with unresectable hepatocellular carcinoma. The 1-, 2-, 3-, 4-, and 5-year survival rates were 55.6%, 31.7%, 16.3%, 8.7%, and 2.9%, respectively, while the median survival was 413 days, and 20 patients survived longer than 3 years after the first lipiodolization. Our study demonstrated that the factors for a comparatively good prognosis were as follows: patient older than 50 years, nodular type hepatocellular carcinoma <5 cm in diameter, negative tumor invasion of portal vein, < 10 intrahepatic metastases, serum alpha-fetoprotein level <400 ng/ml, and Okuda stage I. Lipiodolization did not cure hepatocellular carcinoma. It did, however, in this study, achieve a prolongation of the patient's Survival.