Effect of lipid bilayer alteration on tr
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Ramesh Panchagnula; Hariraghuram Desu; Amit Jain; Sateesh Khandavilli
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Article
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2004
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John Wiley and Sons
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English
⚖ 98 KB
Skin forms an excellent barrier against drug permeation, due to the rigid lamellar structure of the stratum corneum (SC) lipids. Poor permeability of drugs can be enhanced through alteration in partition and diffusion coefficients, or concentration gradient of drug with an appropriate choice of solv