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Lipids, lipophilic drugs, and oral drug delivery—Some emerging concepts

✍ Scribed by William N. Charman


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
168 KB
Volume
89
Category
Article
ISSN
0022-3549

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Skin forms an excellent barrier against drug permeation, due to the rigid lamellar structure of the stratum corneum (SC) lipids. Poor permeability of drugs can be enhanced through alteration in partition and diffusion coefficients, or concentration gradient of drug with an appropriate choice of solv