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Lipid phase transitions in membranes involving intrinsic periodic curvature

✍ Scribed by K. Larsson

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
229 KB
Volume
49
Category
Article
ISSN
0009-3084

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✦ Synopsis

A conformation of the lipid bilayer of membranes is proposed, with periodic curvature corresponding to the minimal surface structure of cubic lipid phases. Evidence is given indicating that activities of lipid synthesis/modification enzymes embedded in the membrane are controlled by the lateral "packing-pressure", so that the lipid bilayer is close to a transition from the lameliar (La) type of conformation to this periodically curved conformation. Such a phase transition mechanism is assumed to be involved in numerous cooperative membrane functions.

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