Lipid metabolism and concentration of adenine nucleotides in the heart muscle in experimental aortic stenosis

Regulation of and intervention into the

Regulation of and intervention into the oxidative pentose phosphate pathway and adenine nucleotide metabolism in the heart

✍ Heinz-Gerd Zimmer 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 812 KB

The capacity of the oxidative pentose pathway (PPP) in the heart is limited, since the activity of glucose-6-phosphate dehydrogenase (G-6-PD), the first and regulating enzyme of this pathway, is very low. Two mechanisms are involved in the regulation of this pathway. Under normal conditions, G-6-PD