Lipid intermediates in chronically volume-overloaded rat hearts
β Scribed by C. Bowe; J. Nzonzi; A. Corsin; J. Moravec; D. Feuvray
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 454 KB
- Volume
- 402
- Category
- Article
- ISSN
- 0031-6768
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π SIMILAR VOLUMES
## Abstract Chronic volume overload leads to cardiac hypertrophy and later to heart failure (HF), which are both associated with increased risk of cardiac arrhythmias. The goal of this study was to describe changes in myocardial morphology and to characterize arrhythmogenic substrate in rat model o
It has been suggested that oxygen free radicals (OFR) depress the excitation-contraction coupling in cardiac muscle. It is possible that a decrease in the cardiac contractility in the failing heart may be due to an increased OFR producing activity of polymorphonuclear (PMN) leukocytes. We studied th