𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Lipid-bound sugars in malignant human breast tumors

✍ Scribed by Ana Rosa Santa Cruza; Luis A. Quesada Allue; Alberto Baldi

Book ID
104673219
Publisher
Springer
Year
1983
Tongue
English
Weight
854 KB
Volume
56
Category
Article
ISSN
0300-8177

No coin nor oath required. For personal study only.

✦ Synopsis

Microsomal preparations from malignant human breast tumors catalyzed the transfer of mannose and glucose from GDP-[14C]-Man and UDP-[14C]-Glc into lipid-linked sugars and glycoprotein-like substances. As judged by several criteria the obtained lipid-linked monosaccharides behaved as dolichyl phosphate mannose and dolichyl phosphate glucose whereas lipid-linked oligosaccharides behaved as polyprenyl diphosphate derivatives. The optimum conditions for mannosyl- and glucosyl-transfer reactions and the effect of dolichyl phosphate, detergent and EDTA on incubation mixture were described.

πŸ“œ SIMILAR VOLUMES

Lipid-bound sugars in Rhizobium meliloti
Lipid-bound sugars in Rhizobium meliloti
✍ Marcelo E. Tolmasky; Roberto J. Staneloni; Rodolfo A. Ugalde; Luis F. Leloir πŸ“‚ Article πŸ“… 1980 πŸ› Elsevier Science 🌐 English βš– 575 KB
The utilization of [3H] sugars by non-ma
The utilization of [3H] sugars by non-malignant and malignant human breast
✍ Rosemary A. Walker; P. R. Sanderson; Sheila J. Day πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 823 KB

The utilization of [3H] sugars and leucine by non-malignant and malignant human breast has been assessed using an organ culture technique with subsequent tissue autoradiography. The uptake of sugars by normal and hyperplastic breast was generally constant, with some differences observed in the utili