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Lipase enhanced catalytic efficiency in lactonisation reactions

โœ Scribed by Carlo Bonini; Cinzia Cazzato; Enrico Cernia; Cleofe Palocci; Simonetta Soro; Licia Viggiani


Book ID
114395677
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
63 KB
Volume
16
Category
Article
ISSN
1381-1177

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An improved, chemoselective hydrogenolysis method has been developed. By employing a solvent-acid combination (i.e., DMF-aq HCl) we were able to favor debenzylation rather than aromatic hydrogenation and acid-mediated bond cleavage which are the two main drawbacks of these reactions. The generality