𝔖 Bobbio Scriptorium
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Lipase-catalyzed synthesis of oleic acid esters of polyethylene glycol 400

✍ Scribed by Giselle G. Janssen; Michael J. Haas

Book ID
105041002
Publisher
Springer Netherlands
Year
1994
Tongue
English
Weight
371 KB
Volume
16
Category
Article
ISSN
0141-5492

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Monomethoxypolyethylene glycols (PEG) of molecular masses 1900 and 5000 were activated using p-nitrophenyl chloroformate to form PEGnitrophenyl carbonates (activated PEG) with high yield (96-98%). The activated PEG was covalently attached to Candida rugosa lipase. Increasing the molar ratio of activ