Lipase-catalyzed regioselective acylation of diosgenyl saponins
β Scribed by Biao Yu; Guowen Xing; Yongzheng Hui; Xiuwen Han
- Book ID
- 104231112
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 85 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Diosgenyl saponins were regioselectively acylated by Novozyme 435 with vinyl esters as acylating agents in THF to afford the corresponding mono-or diacyl diosgenyl saponins.
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The enzymatic synthesis of 6-O-lauroylsucrose and 6-O-palmitoylsucrose was performed by transesterification of sucrose with the corresponding vinyl esters in a medium constituted by two solvents. More specifically, the acylation was carried out in 2-methyl-2-butanol (tertamyl alcohol) containing a l