✦ LIBER ✦
Lipase-Catalysed Regioselective Acylations in Combination with Regioselective Glycosylations as a Strategy for the Synthesis of Oligosaccharides: Synthesis of a Series of Fucosyllactose Building Blocks
✍ Scribed by Anna Rencurosi; Laura Poletti; Giovanni Russo; Luigi Lay
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 196 KB
- Volume
- 2003
- Category
- Article
- ISSN
- 1434-193X
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✦ Synopsis
Abstract
A family of five regioisomeric protected fucosyllactoses has been synthesised in only 14 overall steps from the easily available benzyllactoside. The adopted strategy combines enzymatic regioselective protection, introduction of orthogonal protecting groups and regioselective glycosylations on partially unprotected lactosidic acceptors. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)