Lipase-catalysed kinetic resolution of secondary alcohols with improved enantioselectivity in propylene carbonate
β Scribed by Xiao-Mei Wu; Wei Sun; Jia-Ying Xin; Chun-Gu Xia
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 218 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1573-0972
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π SIMILAR VOLUMES
The use of S-ethyl du 'oo&moate as acyl donor in resolution of secondary alcohols by lipase catalysed transeskfkation, resulted in an efficient displacement of rhe equilibrium towards esterification of the alcohol. A lii (component B) from Can&a antarctica was used 89 the catalyst. On a semi-prepara
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Normally many lipases are efficient catalysts for the acetylation of alcohols with vinyl acetate. Unexpectedly, we found that some sterically hindered secondary alcohols react slowly to yield hemiacetal esters as mixtures of diastereomers. Their formation can be explained by the reaction of the alco