Lipase AK-Mediated Synthesis of Both Antipodes of 2-Phenyl- and 2-(1-Naphthyl)cyclohexanols in Enantiomerically Pure Form.

Enzymes in organic synthesis, 25. Lipase

Enzymes in organic synthesis, 25. Lipase-catalyzed sequential esterification of (±)-2-methylbutanedioic anhydride — a biocatalytical access to an enantiomerically pure 1-monoester of (S)-2-methylbutanedioic acid

✍ Ozegowski, Rüdiger ;Kunath, Annamarie ;Schick, Hans 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 462 KB 👁 1 views

## Abstract The preparation of enantiomerically pure 1‐(2‐methylpropyl) 4‐hydrogen (__S__)‐2‐methylbutanedioate (__ent__‐3) by an enzyme‐catalyzed sequential esterification of (±)‐2‐methylbutanedioic anhydride (__rac__‐1) demands two different enzymes. Lipozyme, a lipase from __Mucor miehei__, was