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Links between replication, recombination and genome instability in eukaryotes

✍ Scribed by Hernan Flores-Rozas; Richard D Kolodner

Book ID
114326670
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
154 KB
Volume
25
Category
Article
ISSN
0968-0004

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## Abstract The tumor suppressor p53 has long been known to play a central role in maintaining a stable genome in the face of toxic insults through its role in promoting cell‐cycle checkpoints, DNA repair, and apoptosis. However, p53 null cells still retain some function of certain checkpoint and r