Linked loci in chromosome 1 (FXIIIB, HF, PEPC) and their variability in Brazilian Indians
✍ Scribed by J. Kömpf; Ch. Luckenbach; D. Krczal; F. M. Salzano; S. M. Callegari-Jacques
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 377 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1042-0533
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✦ Synopsis
A total of 352 individuals living in seven localities of two Brazilian Indian groups (Macushi and Igana River Indians) were variously studied for coagulation factor XIIIB, human factor H, and a new polymorphism of peptidase C. No significant interor intra-tribal differences were found for the FXIIIB alleles, the frequencies varying around 95% for F133*3 and 5% for F133"l. Results for HF were heterogeneous, HF*A presenting a much higher frequency among the Macushi (32%) than among the Icana River Indians (9%). Intratribal differences were also found among both groups. Linkage disequilibrium exists between alleles of these two systems (0.03 ? 0.01). These are the first results for human factor H obtained among Amerindians. The data for PEPC were limited to the Iqana River Indians. There is heterogeneity among the three localities sampled and evidence of moderate linkage disequilibrium between markers in this