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Linkage Studies of the Esterase D and Retinoblastoma Genes to Canine Copper Toxicosis: A Model for Wilson Disease

✍ Scribed by Vilma Yuzbasiyan-Gurkan; Shelly Wagnitz; Susan Halloran Blanton; George J. Brewer


Book ID
117979479
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
332 KB
Volume
15
Category
Article
ISSN
0888-7543

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Wilson disease (WD) is an inherited disorder of copper metabolism that affects the brain, liver, and other organs. Our group recently reported close linkage between the locus for WD and a polymorphic red cell enzyme, esterase D (EsD), in a large inbred Israeli-Arab lineage. We have subsequently stud