## Abstract Previous results from our genetic analyses using pedigrees from a French Canadian population suggested that the interval delimited by markers D12S86 and D12S378 on chromosome 12 was the most probable genomic region to contain a susceptibility gene for affective disorders. Here we presen
Linkage studies of bipolar disorder in the region of the Darier's disease gene on chromosome 12q23-24.1
✍ Scribed by Dawson, Elisabeth ;Parfitt, Elizabeth ;Roberts, Queta ;Daniels, Jo ;Lim, Lionel ;Sham, Pak ;Nöthen, Markus ;Propping, Peter ;Lanczik, Mario ;Maier, Wolfgang ;Reuner, Ulrike ;Weissenbach, Jean ;Gill, Michael ;Powell, John ;McGuffin, Peter ;Owen, Mike ;Craddock, Nick
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 939 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We completed a genome-wide scan for susceptibility loci for bipolar affective disorders in families derived from a rather homogeneous population in the Province of Que ´bec. The genetic homogeneity of this population stems from the migration of founding families into this relatively isolated area o
## Abstract Three linkage studies of families with multiple cases of bipolar disorder and/or unipolar affective disorder have confirmed the involvement of the chromosome 1p36 region in the etiology of affective disorders with LOD scores of 2.7, 3.6, and 3.97. We investigated the protein kinase C ze