Linkage ofPep-2andApkon mouse chromosome 10

✍ Scribed by James E. Womack; Shawn Ashley; Lois B. Barnett; Susan E. Lewis

• Publisher: Springer
• Year: 1986
• Tongue: English
• Weight: 331 KB
• Volume: 24
• Category: Article
• ISSN: 0006-2928
• DOI: 10.1007/bf00499005

✦ Synopsis

An ethylnitrosourea (ENU)-induced electrophoretic variant of mouse PEP-2, a tripeptidase, has been used to determine the location of the structural gene on chromosome 10. Gene order and recombination frequencies were estimated as Apk-21.8 +/- 3.9%-Pep-2-3.7 +/- 2.1%-Sl. Methods for rapid determination of Apk and Pep-2 alleles by cellulose acetate electrophoresis and a valuable linkage testing stock carrying the unique Apkm and Pep-2b alleles are described.