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Linkage Disequilibrium and Heritability of Copy-Number Polymorphisms within Duplicated Regions of the Human Genome

✍ Scribed by Devin P. Locke; Andrew J. Sharp; Steven A. McCarroll; Sean D. McGrath; Tera L. Newman; Ze Cheng; Stuart Schwartz; Donna G. Albertson; Daniel Pinkel; David M. Altshuler; Evan E. Eichler


Book ID
117854852
Publisher
American Society of Human Genetics
Year
2006
Tongue
English
Weight
556 KB
Volume
79
Category
Article
ISSN
0002-9297

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In the past few years the number of copy number variants (CNVs) identified in the human genome has increased significantly, but our understanding of the functional impact of CNVs is still limited. Clinically significant variations cannot easily be distinguished from benign, complicating interpretati