CYP17 encodes the enzyme cytochrome P-450c17β£, which mediates both 17β£-hydroxylase and 17,20-lyase in the steroid biosynthesis pathway. A polymorphism in the 5 promoter region of the CYP17 gene has been described. Steroid hormones, especially androgens, are believed to play a key role in the etiolog
Linkage and association of CYP17 gene in hereditary and sporadic prostate cancer
β Scribed by Bao-li Chang; Siqun L. Zheng; Sarah D. Isaacs; Kathy E. Wiley; John D. Carpten; Gregory A. Hawkins; Eugene R. Bleecker; Patrick C. Walsh; Jeffrey M. Trent; Deborah A. Meyers; William B. Isaacs; Jianfeng Xu
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- French
- Weight
- 81 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0020-7136
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