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Linkage analysis of the receptor gene and MODY

✍ Scribed by S. O'Rahilly

Publisher
Springer
Year
1988
Tongue
English
Weight
272 KB
Volume
31
Category
Article
ISSN
0012-186X

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DNA haplotype analysis suggests linkage
DNA haplotype analysis suggests linkage disequilibrium in the human insulin receptor gene
✍ Margareta Sten-Linder; Marianne Olsson; Lennart Iselius; Holger Luthman; Suad Ef πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 574 KB

Haplotypes of the insulin receptor gene were resolved in parents from Scandinavian nuclear families by studying the segregation of seven restriction fragment length polymorphisms (RFLPs). Of 97 unrelated parents, 41 had non-insulin-dependent diabetes mellitus (NIDDM). Considerable linkage disequilib