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Linkage analysis of plasma amyloid β protein in typical late onset Alzheimer disease (load)

✍ Scribed by Nilufer Ertekin Taner; Neill Graff-Radford; Linda H. Younkin; Michael L. Hutton; Steven G. Younkin


Book ID
117411533
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
190 KB
Volume
21
Category
Article
ISSN
0197-4580

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Plasma amyloid beta42 peptide (Abeta42) levels are significantly elevated in all genetic forms of early-onset Alzheimer's disease caused by familial Alzheimer's disease mutations or Down's syndrome. Moreover, recent studies have determined that both plasma Abeta42 and Abeta40 levels are significantl