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Linkage analysis for the diagnosis of autosomal dominant polycystic kidney disease, and for the determination of genetic heterogeneity in Italian families

✍ Scribed by Alberto Turco; Bernard Peissel; Linda Gammaro; Giuseppe Maschio; Pier Franco Pignatti


Book ID
115090253
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
650 KB
Volume
40
Category
Article
ISSN
0009-9163

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Genetic linkage studies of autosomal dom
✍ Shrawan Kumar; William J. Kimberling; Patricia A. Gabow; Judy B. Kenyon πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 410 KB

Polycystic kidney disease (PKD) is a common autosomal dominant genetic disorder caused by mutation in at least two different gene loci. The PKD1 gene has been localized on the short arm of chromosome 16. The location of a second genetic locus in the human genome is not yet known. A large PKD kindred