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Limits to chemical hormesis as a dose–response model in health risk assessment

✍ Scribed by Mushak, Paul

Book ID
123430438
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
233 KB
Volume
443
Category
Article
ISSN
0048-9697

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Here we describe a random effects threshold dose-response model for clustered binary-response data from developmental toxicity studies. For our model we assume that a hormetic effect occurs in addition to a threshold effect. Therefore, the dose-response curve is based on two components: relationship