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Limited usage of T-cell receptor β chains and sequences of the complementarity determining region 3 of lymphocytes infiltrating in the liver of autoimmune hepatitis

✍ Scribed by Yuji Hoshino; Nobuyuki Enomoto; Namiki Izumi; Masayuki Kurosaki; Fumiaki Marumo; Chifumi Sato


Book ID
119155958
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
741 KB
Volume
22
Category
Article
ISSN
0270-9139

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Limited usage of T-Cell receptor β chain
✍ Yuji Hoshino; Nobuyuki Enomoto; Namiki Izumi; Masayuki Kurosaki; Fumiaki Marumo; 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 658 KB

To study the role of antigen-specific T lymphocytes in the pathogenesis of autoimmune hepatitis, messenger RNA of T-cell receptors (TCR) was analyzed in liver biopsy specimens from four patients with autoimmune hepatitis. Using the TCR P-chain variable region family specific oligonucleotides, a rema