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Limited penetration of posaconazole into cerebrospinal fluid in an allogeneic stem cell recipient with invasive pulmonary aspergillosis

✍ Scribed by Reinwald, M; Uharek, L; Lampe, D; Grobosch, T; Thiel, E; Schwartz, S

Book ID: 109840756
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 83 KB
Volume: 44
Category: Article
ISSN: 0007-1188
DOI: 10.1038/bmt.2009.17

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## Abstract ## BACKGROUND. Invasive aspergillosis (IA) is a leading cause of death in patients with leukemia and those who have undergone hematopoietic stem cell transplantation. Laboratory studies have demonstrated that iron is essential for __Aspergillus__ growth and virulence. ## METHODS. In