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Limited Energy Supply in Müller Cells Alters Glutamate Uptake

✍ Scribed by Toft-Kehler, Anne Katrine; Skytt, Dorte Marie; Poulsen, Kristian Arild; Brændstrup, Charlotte Taul; Gegelashvili, Georgi; Waagepetersen, Helle; Kolko, Miriam


Book ID
125366831
Publisher
Springer
Year
2014
Tongue
English
Weight
517 KB
Volume
39
Category
Article
ISSN
0364-3190

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We characterized morphological effects of the endogenous excitotoxin, glutamate in ex vivo retinal segments prepared from 30-day-old rats. Initial changes induced by glutamate consisted of reversible, sodium-dependent Mu ¨ller cell swelling. This glial swelling was mimicked by glutamate transport su