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Limitations of the human tumour xenograft system in individual patient drug sensitivity testing

โœ Scribed by Bailey, M J; Jones, A J; Shorthouse, A J; Raghaven, D; Selby, P; Gibbs, J; Peckham, M J


Book ID
109835566
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
491 KB
Volume
50
Category
Article
ISSN
0007-0920

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Xenografts in pharmacologically immunosu
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A human tumor xenograft model using pharmacologically immunosuppressed mice was assessed for its suitability to test preclinically the sensitivity of colorectal carcinomas, bone sarcomas and melanomas against anticancer agents. Besides ionizing radiation, 14 cytotoxic drugs including 5-fluorouracil