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Limitations of homology searching for identification of T-cell antigens with library derived mimicry epitopes

✍ Scribed by Hoebert S. Hiemstra; Peter A. van Veelen; Annemieke Geluk; Nanette C. Schloot; Rene R.P. de Vries; Tom H.M. Ottenhoff; Bart O. Roep; Jan W. Drijfhout


Book ID
117433619
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
117 KB
Volume
18
Category
Article
ISSN
0264-410X

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## Abstract Multi‐component glycopeptide libraries and single glycopeptides were used for immunization of mice with the aim of inducing strong T helper cell responses to the repetitive sequence of MUC1 expressed by human tumor cells. The glycopeptides and glycopeptide libraries were modeled upon th