✦ LIBER ✦

Limitations of flow cytometric DNA analysis for the diagnosis of bladder cancer

✍ Scribed by Michel A. Boileau; Douglas Swartz; Karmen L. Schmidt; Waldemar A. Schmidt

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 655 KB
Volume: 40
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930400313

No coin nor oath required. For personal study only.

✦ Synopsis

Flow cytometric analysis was done on exfoliated urothelial cells from 11 control patients and 3 1 patients with transitional cell carcinoma: 9 grade I, 11 grade 11, and 11 grade 111. The determination of aneuploidy by DNA analysis did not provide identification of low-grade tumor cells. Other flow cytometric parameters of cellular change such as cell size, nuclear size, nuclearlcytoplasmic ratio, or cell refractivity may provide better identification of low-grade lesions.

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