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LIGNIN: A BILE-SALT SEQUESTRATING AGENT

✍ Scribed by Eastwood, M.A.; Girdwood, R.H.


Book ID
122929738
Publisher
The Lancet
Year
1968
Tongue
English
Weight
466 KB
Volume
292
Category
Article
ISSN
0140-6736

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Liver receptor homolog-1 is critical for
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Liver receptor homolog-1 (LRH-1) is a nuclear receptor that controls a variety of metabolic pathways. In cultured cells, LRH-1 induces the expression of CYP7A1 and CYP8B1, key enzymes in bile salt synthesis. However, hepatic Cyp7a1 mRNA levels were not reduced upon hepatocyte-specific Lrh-1 deletion