The structures and conformations of three new lignans, wikstrone (1), wikstroemol (2), and wikstroemone (3) -isolated from the aerial parts of Wikstroemia hainanensis -were determined, together with those of twelve known compounds, including erythro-guaiacylglycerol-b-O-4'-sinapyl ether (4). The configuration of 4, falsely assigned in the literature (threo configuration), was redetermined, and the compound was identified as erythro-guaiacylglycerol-b-O-4'-sinapyl ether. Introduction. -The genus Wikstroemia belongs to the family Thymelaeaceae. Several species of this genus were shown to produce biologically active daphnane-[1] and tigliane-type [2] diterpenoids, lignans [3], biflavonoids [3b] [4], and bicoumarins [3]. Wikstroemia hainanensis MERR., a tiny shrub indigenous to Hainan Province, China, has not been chemically investigated previously. In the current paper, three new lignans, wikstrone (1), wikstroemol (2), and wikstroemone (3), along with twelve known compounds, erythro-guaiacylglycerol-b-O-4'-sinapyl ether ( 4), 4-hydroxytrans-cinnamic acid, (+)-pinoresinol, (+)-medioresinol, (+)-syringaresinol, (+)-nortrachelogenin, (ร)-lariciresinol, ficusesquilignan A, sitosterol, hederagenin, umbelliferone, and daphnoretin, were isolated from the aerial parts of W. hainanensis, and structurally identified by spectroscopic methods.