𝔖 Bobbio Scriptorium
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Lignans from the Bark of Zanthoxylum planispinum

✍ Scribed by Guang-Zhong Yang; Yun Hu; Bo Yang; Yu Chen

Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
177 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

A new dimeric lignan, named biplanispine A (1) which represents the first example of a dimeric 2,6‐diaryl‐3,7‐dioxabicyclo[3.3.0]octane skeleton from a Rutaceae plant, together with 13 known lignans 2–14, was isolated from the bark of Zanthoxylum planispinum. Their structures were elucidated by spectroscopic methods, especially 2D‐NMR techniques. All isolated compounds were evaluated for their antibacterial activities by the disc diffusion method. Compounds 7 and 9 showed interesting antibacterial activities at 200 μg/disc; they were as effective as kanamycin sulfate at 10 μg/disc against Staphylococcus aureus and Bacillus subtilis.

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