Light-dependent changes in cytoplasmic aspartate aminotransferase activity in rod spherules of the rat retina

✍ Scribed by R. Gebhard

• Book ID: 104692767
• Publisher: Springer
• Year: 1991
• Tongue: English
• Weight: 384 KB
• Volume: 96
• Category: Article
• ISSN: 1432-119X
• DOI: 10.1007/bf00267080

✦ Synopsis

The cytoplasmic activity of the glutamate synthesizing enzyme aspartate aminotransferase (c-AAT) has been investigated on the ultrastructure level in rod spherules of light and dark adapted rat retinae using cytochemistry. Although most rod terminals react negatively, in a subpopulation of rods a weak activity, which is observed in light adapted retinae, is markedly increased under dark conditions. This indicates, that in addition to cones, some rods might use glutamate as their transmitter as well.