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Light-Controlled Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Live Cells

โœ Scribed by Zhang, Kai; Duan, Liting; Lin, Ziliang; Sung, Kijung; Osakada, Yasuko; Cui, Bianxiao


Book ID
123290540
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
40 KB
Volume
104
Category
Article
ISSN
0006-3495

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Multiple studies demonstrate that manganese (Mn) exposure potentiates inflammatory mediator output from activated glia; this increased output is associated with enhanced mitogen activated protein kinase (MAPK: p38, ERK and JNK) activity. We hypothesized that Mn activates MAPK by activating the kinas