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Light chain heterogeneity of 19s and 7s anti-γ-globulins in rheumatoid arthritis and subacute bacterial endocarditis

✍ Scribed by Dennis A. Carson; Simon Lawrance


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
272 KB
Volume
21
Category
Article
ISSN
0004-3591

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✦ Synopsis


Abstract

Both 19S and 7S anti‐γ‐globulins in rheumatoid arthritis sera are enriched in kappa light chain bearing antibody molecules when compared to total 19S and 7S globulins from the same individuals. In patients with subacute bacterial endocarditis 19S anti‐γ‐globulins are also, to a degree, enriched in kappa light chains, whereas the 7S anti‐γ‐globulins have kappa to lambda light chain ratios indistinguishable from total 7S globulin.